One of the things on the Preponomicon that I am trying to get into the green is some OTC medications. Presumably, these things are going to sit on a shelf for, at least, several years. Does aspirin turn into some sort of toxic acid a few years after its ‘Best By’ date?
Just like food, medication is required by law to have an expiration date on its packaging. But how long past that date can you keep using your over-the-counter and prescription drugs? And is it safe to take expired medicine?
INSIDER talked to medical experts to find out how long you can keep using some common medications after opening them.
The answer, it seems, is ” a usefully long time”. But, honestly, this is one of those times where I’m probably going to disregard the common advice, as well as the small financial hit, and simply throw out and replace my 500-tablet bottle of ibuprofin every five years.
Hunter S. Thompson’s Continental breakfast
However, up until a few years ago I was still using a gigantic bottle of Advil that I’d bought at CostCo with an ‘Expiration date’ in 1997. Made my headaches go away just fine.
TL,DR: your Tylenol, Advil, and aspirin are GTG for about 5 years.
ETA: I was sent this in email:
The military did a study back in the 80’s examining the bioactivity of stored drugs… And found that almost all of them were good to go years after their expiration dates. These are drugs that were stored in climate controlled warehouses, in original factory packaging.
ProTip: Don’t buy one big bottle of a drug, buy lots of little ones… Drugs are hermetically sealed at the factory, and once you open them and start shaking things out, moisture gets in and starts degrading the drug. Not to mention whatever you may introduce with your finger..
For drug storage, put the unopened drugs in a refrigerator – don’t freeze them. Why keep them cool? In general (rule of thumb time) for every 10-degree C reduction in temperature a chemical process (like a drug, degrading) experiences, the rate of the process reduces by 1/2. So, your drugs will last about 4 times longer in the refrigerator at 2-c, then at room temperature at 22-c.
Why not freeze them? Because they may degrade (especially liquid or ointment products) and separate (the various components freeze at different temperatures). When they thaw, they melt at different temps too, and don’t reconstitute. This is ESPECIALLY important for drugs like insulin, a protein: Freezing the protein breaks it apart, and then it is done. No longer useful… So, cold: Not frozen.
The military did a study back in the 80’s examining the bioactivity of stored drugs… And found that almost all of them were good to go years after their expiration dates. These are drugs that were stored in climate controlled warehouses, in original factory packaging.
Disclaimer: I am a physician. I am NOT your physician. This is not medical advice.
https://www.propublica.org/article/the-myth-of-drug-expiration-dates
https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/expiration-dating-extension